The University of Washington Alpha Chapter of Phi Beta Kappa was established in 1914. Since then, the chapter has grown to include members such as physician and NASA astronaut Michael Barratt and Nobel Prize–winning doctor George Herbert Hitchings.

The Beta of Washington chapter was founded at Whitman College in 1920. The chapter hosts an annual luncheon with a guest speaker during commencement weekend to honor new members and regularly hosts Phi Beta Kappa Visiting Scholars.

Washington State University's Gamma of Washington Chapter was established in 1928, making it one of the first founded at a land-grant university. The chapter offers two awards to students: the Sidney G. Hacker Phi Beta Kappa Scholarship and the Phi Beta Kappa Scholarship.  

The University of Puget Sound Delta Chapter of Phi Beta Kappa was founded in 1986. The chapter offers several awards and scholarships — Campbell Scholarships, James Slater Scholarships, and PSA-PBK Scholarships — to students.